This omission is all the more remarkable given that, as Chargaff also noted, Miescher's discovery of nucleic acids was unique among the discoveries of the four major cellular components (i.e., proteins, lipids, polysaccharides, and nucleic acids) in that it could be "dated precisely. For instance, in a 1971 essay on the history of nucleic acid research, Erwin Chargaff noted that in a 1961 historical account of nineteenth-century science, Charles Darwin was mentioned 31 times, Thomas Huxley 14 times, but Miescher not even once. More than 50 years passed before the significance of Miescher's discovery of nucleic acids was widely appreciated by the scientific community. Sensing the importance of his findings, Miescher wrote, "It seems probable to me that a whole family of such slightly varying phosphorous-containing substances will appear, as a group of nucleins, equivalent to proteins" (Wolf, 2003). But when he came across a substance from the cell nuclei that had chemical properties unlike any protein, including a much higher phosphorous content and resistance to proteolysis (protein digestion), Miescher realized that he had discovered a new substance (Dahm, 2008). Miescher thus made arrangements for a local surgical clinic to send him used, pus-coated patient bandages once he received the bandages, he planned to wash them, filter out the leukocytes, and extract and identify the various proteins within the white blood cells. (The term "nuclein" was later changed to " nucleic acid" and eventually to " deoxyribonucleic acid," or "DNA.") Miescher's plan was to isolate and characterize not the nuclein (which nobody at that time realized existed) but instead the protein components of leukocytes (white blood cells). In memory of Ian Thomas Strickler, please visit our floral store.Although few people realize it, 1869 was a landmark year in genetic research, because it was the year in which Swiss physiological chemist Friedrich Miescher first identified what he called "nuclein" inside the nuclei of human white blood cells. The family will receive friends on Tuesday, July 11, from 6-8 p.m. Ian also leaves behind two fur babies, Baloo and Mowgli.Ī funeral service with honors will be held on Thursday, July 13, at 3 p.m.
While living in Weymouth, MA, Ian was a Special State Police Officer (SSPO) at Massachusetts General Hospital for seven years, where he met his wife, Stephanie. Ian was passionate about safety, working as security and moving through ranks to Security Supervisor. He was also a huge sports fan, the Bruins, Celtics, Red Sox, and Alabama, Roll Tide! Ian played baseball in high school and played in Softball Leagues while living in Boston. He participated in and loved the James Madison Marching Royal Dukes. Ian was a graduate of Luray High School in 2005 and James Madison University in 2011. Watson III of Ranson, WV, and James Strickler of Luray. Ian was preceded in death by grandparents William and Margaret Stunkle of Ranson, WV, and Franklin Strickler of Luray, as well as Uncles James E. He is also survived by his grandmother, Frances Strickler of Luray Aunt Barbara Watson of Ranson, WV and numerous uncles, aunts and cousins of Luray: Phillip and Lynn Strickler, Kimberly Strickler, Jason and Jennifer Strickler, Jami and David Sedwick, Dylan and Sarah Cooper, Joseph and Felisha Strickler, and of West Virginia: Aaron Watson and Jamie Corrine, Charles Town, Adam and Meghan Watson, Charles Town, and Ethan and Katelyn Watson of Martinsburg. and Gail Fiandaca of Brockton, MA and her siblings, Charles (C.J.) Fiandaca III of Brockton, MA, and Andrea Fiandaca and John Barrett of Kingston, MA. Ian is survived by his loving wife, Stephanie Fiandaca-Strickler her parents Charles Jr. His parents are David and Alice Strickler and sister is Samantha Strickler of Luray. Ian was born August 7, 1987, in Ranson, West Virginia. Ian Thomas Strickler, 35, of Luray, died July 5, 2023, in the line of duty as Recruit Firefighter with Frederick County Fire and Rescue.
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